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Poma A, Vecchiotti G, Colafarina S, Zarivi O, Aloisi M, Arrizza L, Chichiricco G, Di Carlo P

The following table represents the RNI for the different age groups

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These melanocortin ligands activate the MC4R on neurons in the paraventricular nucleus of the hypothalamus 28 , thereby suppressing appetite, promoting satiety and stimulating energy expenditure 33 (Figure 2)